PL341/343 Series Precision Polarimeter (PerkinElmer)

Based on decades of research and manufacturing experience in precision polarimeters, PerkinElmer has introduced the Model 341/343 automatic precision polarimeter to meet the applications in the above areas. The Model 341/343 polarimeter adopts the principle of automatically rotating the polarizer to the optical null position, providing the highest accuracy and precision. Monochromatic light passes through the polarizer, sample cell, and analyzer to the photomultiplier tube. At the optical null position, the plane of polarization of the analyzer is perpendicular to the plane of polarization of the incoming light source. When an optically active sample is placed in the light path, the servo feedback system rotates the analyzer until it returns once again to the optical null position. This angle of rotation is measured by an optical encoder with a resolution of 0.1 millidegree. The results are displayed on a vacuum fluorescent display, along with the direction of rotation. Gain adjustment and balance control are also performed automatically. For routine analysis, all you need to do is select the wavelength, insert the sample, and read the result (or print it).

* Characterization of newly synthesized products * Quality control of pharmaceutical products * Monitoring and control of enzymatic reactions * Precise quantitative detection in the sugar industry * Selective detection of optically active substances in components separated by high-performance liquid chromatography

◆ Model 341 General-purpose precision polarimeter, dual light sources Na lamp and Hg lamp, dual Glan-Taylor polarizers, can be used not only for routine quality control, but is also particularly suitable for research work. With the addition of filters it can be extended to the UV region, and can also be used as a polarimetric detector for HPLC. ◆ Model 343 Uses only one interference filter to precisely select the 589nm wavelength of the Na spectral lamp, for economical and rational routine polarimetric determination. ◆ Model 343plus Dual-wavelength polarimeter; in addition to the conventional 589nm wavelength, it is also equipped with a green spectral line 546nm filter for the mercury lamp. ◆ Model 343S A dedicated model for the sugar industry, usable for quality inspection in the sugar-making process, equipped with the mercury lamp 546nm wavelength. ◆ Model 341LC A dedicated HPLC detector kit for the Model 341 polarimeter. Includes the Model 341 polarimeter, plus an additional 302nm filter and a specially made HPLC flow cell, for use as a polarimetric detector for HPLC. Multiple-format result reports Press one key to display the following results; in addition, the following can also be read: ◆ Rotation angle ◆ Specific rotation ◆ Molar rotation ◆ Operator-selected concentration factor ◆ Sugar content (expressed in International Sugar Scale °Z) Energy (radiation intensity) at measurement Standard deviation over the integration (averaging) calculation period Analysis reports comply with GLP requirements: The Model 341 polarimeter provides a complete analysis report and can output it to a printer or transmit it to a computer. This report includes all the data of the test information and can be recalled or re-evaluated. In addition to the actual measurement results, the report also displays the wavelength used, sample temperature, sample number, measurement date, and the factory serial number of the instrument used. You can add your company or laboratory name, and can write in alphabetic form the characteristics of the sample (such as the raw material number and the name of the substance). When measuring specific rotation or molar rotation, the analysis report can also include the cell length, sample concentration, molar mass and measured optical rotation. For a series of measurements, the results can also be printed in tabular form. The Model 341 supports EPSON, HP laser/inkjet printers or other compatible printers; when output in ASCII format, a wide variety of printers on the market can also be used. Multiple polarimeter cell formats adapt to various application analyses Standard cells and micro cells with different path lengths are available, for example, small-volume micro cells; for a 100mm path length there are respectively 1ml and 350 μl volumes. The polarimeter cell windows are fused with the cell body by a special patented method, so as to keep the windows free from tension. This ensures that the residual optical rotation of the polarimeter cell windows is extremely small and negligible for most applications. For HPLC detection, special flow cells with a path length of 100mm and volumes of respectively 80μl or 40μl can be selected. Automatic instrument calibration function This polarimeter has built-in calibration routine procedures, so that the instrument can operate reliably and to assist in identifying possible sources of error. The 341/343 series polarimeters are shipped from the factory with documents such as the instrument performance specification certificate, test records and measurement parameters. For laboratories that need to periodically verify the accuracy of their various measuring instruments, PerkinElmer offers various stable, easy-to-use quartz standard plates that comply with the recommendations of various national pharmacopoeias for polarimeters. There are primary standards and secondary standards. All standard plates are accompanied by an identification certificate stating their optical rotation at the Na D line (589nm) and at some other Hg spectral lines. These standard plates, together with our precision polarimeters and GLP certification documents, ensure accurate and reliable analysis results. Control software PerkinElmer has newly introduced a set of "PL WinLab" software running in a Windows environment for the 341/343 series polarimeters. This software can fully control the 341/343 series polarimeters, and record and store data. It has programmable wavelength program measurement; for most applications, determinations can be carried out using pre-programmed methods, and dynamic determinations can also be carried out using time-driven methods. The software also includes a program for automatic instrument calibration. High precision and accuracy The working principle of the 341/343 polarimeters ensures an accuracy as high as 0.002° when the optical rotation is <1°. The use of line-spectrum lamps with matching interference filters yields a very pure spectral line, which is a very important advantage for the measurement of substances with high optical rotation. The instrument's automatic gain adjustment and selectable integration time ensure high accuracy even when measuring strongly absorbing samples. High versatility The Model 341 uses multiple interference filters and can precisely provide 5 wavelength spectral lines of the Hg lamp and Na lamp spectra, so as to be suitable for the needs of various measurements. There are also 4 spare positions on the filter holder, into which selected filters can be placed as needed to obtain more mercury lines, and the measurement range can be extended to the UV range (approximately 250nm). It uses high-precision Glan-Taylor polarizers (calcite polarizing prisms with an air gap). To accommodate standard cells or micro cells, two aperture stops are selectable, and 10 different integration time parameters are available for selection. Multiple models adapt to different needs PerkinElmer's precision polarimeter series includes 5 different models. Each model can be used independently; their optical performance specifications are identical, differing only in wavelength. All can be connected to a printer to print out a report format that satisfies GLP/GMP requirements.