Fiber for Arterial Plaque Ablation DMXR-06
Technological progress has greatly advanced medicine, particularly timely and important in interventional treatment. Efforts to find disease-prevention/treatment breakthroughs have prompted research and clinical adoption of new techniques. A new minimally invasive intervention combining hybrid surgery is excimer laser coronary atherectomy. Excimer Laser Coronary Atherectomy (ELCA) treats coronary disease with pulsed near-ultraviolet light at 308 nm, using xenon and hydrogen chloride as active media. Tissue penetration is <50μm. Thrombi, plaque, and related tissues absorb the light and are ablated. Fiber catheters deliver UV pulses to plaque. Absorption triggers photochemical reactions breaking molecular bonds, called photoablation. This nonthermal or low-thermal effect is the main mechanism, reducing arterial-wall injury risk. During ELCA, a laser fiber catheter enters the diseased vessel under X-ray fluoroscopy, followed by repeated laser ablation of thrombus/plaque. Three mechanisms contribute: photochemical action, where absorbed pulses break carbon-carbon double bonds and destroy molecular structure; photothermal action, converting energy into heat that denatures proteins and ruptures cells; and photoacoustic action, with pulse-generated shock waves disrupting thrombi/plaque. Indications include balloon-uncrossable/undilatable lesions, including chronic total occlusions (CTO), stent underexpansion, and in-stent restenosis (ISR). Overall, fiber-catheter-delivered excimer light ablates coronary plaque through photochemical reactions without significant arterial-wall thermal injury, particularly for complex lesions difficult to treat with conventional PCI.
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Overview
Specifications
| Parameter | Value |
|---|---|
| Fiber core diameter | 600 μm |
| Cladding Diameter | 660 μm |
| Coating Diameter | 740 μm |
| Buffer diameter | 960 μm |
| Length | 2.5M/3M |
| Termination type | SMA905 |
| Numerical Aperture (NA) | 0.22 |
| Core Material | Pure silica material |
| Fiber cladding material | Fluorine-doped silica material |
| Coating Material | Acrylic resin |
| Buffer material | Teflon |
| Buffer color | Blue/green/black/white |
| Operating Temperature | -40℃~150ºC |
| Transmission wavelength | 190-1100nm |
| Single-filament transmission efficiency | ≥90% |
| Characteristics | Compliant with biocompatibility requirements |
| Proof-test strength | 100kpsi |
| Fiber Type | Step-index type |
| REACH report | Compliant with standards |
| RoHS report | Compliant with standards |
Datasheet
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Supplier Information
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