Photodynamic Fiber GDL-09
Photodynamic Therapy (PDT) uses light and photosensitizers to generate reactive oxygen species that selectively kill tumor cells. Activated sensitizers produce singlet oxygen and radicals, oxidizing membranes and important molecules. Injected sensitizers accumulate more in tumors than normal tissue. Wavelength-specific illumination, potentially delivered internally by fiber, activates them at the tumor, damaging membrane lipids, DNA, and RNA. The source lists selective tumor necrosis with minimal normal-tissue damage, no special systemic toxicity or drug interactions, compatibility with other treatments, low invasiveness and scarring, use for superficial or fiber-accessible lesions, no cumulative drug toxicity, and repeatability. Limitations include high cost, poor penetration of large tumors, and skin-retained sensitizers causing photosensitivity, requiring avoidance of strong light for 3-4 weeks after treatment.
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Overview
Specifications
| Parameter | Value |
|---|---|
| Fiber core diameter | 1000 μm |
| Cladding Diameter | 1100 μm |
| Coating Diameter | 1350 μm |
| Buffer diameter | 1600 μm |
| Length | 2.5M/3M |
| Termination type | SMA905 |
| Numerical Aperture (NA) | 0.22 |
| Core Material | Pure silica material |
| Fiber cladding material | Fluorine-doped silica material |
| Coating Material | Acrylic resin |
| Buffer material | Teflon |
| Buffer color | Blue/green/black/white |
| Operating Temperature | -40℃~150ºC |
| Transmission wavelength | 190-1100nm/400-2500nm |
| Single-filament transmission efficiency | ≥90% |
| Characteristics | Compliant with biocompatibility requirements |
| Proof-test strength | 100kpsi |
| Fiber Type | Step-index type |
Datasheet
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Supplier Information
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